Investing in the Founder’s Brain

How Protecting Brain Health Can Drive Business Growth by Offsetting the Hidden Costs of Entrepreneurial Superpowers

Diverse business professionals engaged in an active, focused discussion during a collaborative meeting.

Entrepreneurs are among the world’s greatest innovators, but the same cognitive traits that fuel creativity, resilience, and bold decision making can also increase vulnerability to burnout and mental health challenges. In this report, the Wharton Neuroscience Initiative and Econa explore the neuroscience of entrepreneurship, the link between founder wellbeing and business performance, and why investing in brain health is essential for building resilient leaders, stronger companies, and a thriving innovation economy.